Animal rights activists have threatened a series of attacks in London and the first victim, the daughter of a commercial laboratory owner, is in hospital. Gene orders his team not to sleep until those responsible are behind bars. Their first stop is a prison where Robin Elliot, a known animal rights campaigner, is serving time for killing a scientist in the 1970s. Alex is convinced that Robin knows about the planned attacks, but with no contact with the outside world, there doesn't appear to be any way for him to be involved. Robin's eerily prescient knowledge of the future makes Alex think that he could be involved not only with the case, but with her own fate; having heard the voices of ambulancemen, Alex worries that hope is fading for her survival in the present day.

A face from Gene's old stomping ground of Manchester shows up called Jackie Queen. Jackie is a reporter who is investigating teenagers who traveled to London from the north and have disappeared.

After a dead body is found in the canal it is identified as Colin Mitchell. Alex is certain that the dead man's wife Donna is not telling everything and she is determined to uncover the truth. Back in 2008, Alex has surgery to remove the bullet from her brain.

CID find a body buried in concrete as they investigate a drugs drop at a building site. Alex thinks she is getting better and will soon wake up in her own time. Working on the case though starts to clash with her wish to be back home.

After Alex catches an infection back in 2008, she knows the doctors think she wont pull through. Distance grows between Alex and Gene and their relationship is put under the greatest strain yet.