An anguished Syd is forced to recall a repressed childhood memory of her late mother Lynda's flirtation with a neighbor while she nurses a dying elderly woman who struggles to remain alive long enough to reconciliate with her arriving daughter. Elsewhere: Joanie poses as Syd at a pharmaceutical convention in order to get her sister some much-needed drug samples but winds up in jail with a gaggle of hookers; Robbie mistakenly ends up playing a serious game of cards with some mob wiseguys; and Jim turns the house upside down when he becomes obsessed with ousting a playful but evasive mouse.
Syd is about to go and will need therapy to help her leg heal from Encephalitis. Syd finds out her therapist is a man not big on machines. Syd begins working out and over works. Jim takes in dogs that came from Chicago because the owner wasn't found. Andi is stalking Robbie because he wouldn't cheat for her, Syd ignores her body's needs to rest while driving Izzy home and hit a tree. Joannie learns that Bert has girl friend. Syd doesn't feel normal and thinks about quitting medicine.