The casino has reopened. Ed and Mike work on a case of counterfeit casino chips. Per his accountant's suggestion, Danny must sell his father's house. Later, Danny's accountant is part of a poker game where one of the players is a man who robs one of the casino's guests. Monica Mancuso, the new owner, wants a dealer to be fired because he keeps dealing winning hands to the players.

Danny is with blackjack player Gabe Labrador who's wearing a wig and counting cards. The man doesn't want to stop playing and claims he must win big to pay off the men who kidnapped his daughter. Ed, Mike, Danny and a cop from Metro work on the case even though they aren't sure Gabe is telling the truth. Mary seems to still be helping Danny taking care of his dad's stuff. She is still dating Jake. A player who won a lot of money wants to give it back, but then wants it back, then wants to give it again, etc. The crossover starts on Crossing Jordan S05E02 Luck Be a Lady (I).

Sam's whale is named Trey Cooper, a handsome 30-year-old who brought his Great Dane to the casino. There are a lot of dogs around the casino as the Nevada State Dog Show is taking place. Jillian enters the Deline's dog in the competition. Monica and Danny meet with an 80-year-old woman named Dottie. Monica offers 3 million for Dottie's house in order to build a golf course. Things will become complicated when on the demolition site, construction workers find a skeleton. A CSI believes it could be the body of Seymour "Blue Jaw" Magoon, a member of a 40s gang called Murder Inc. Mike helps a couple who's "stuck" together. Jake seems to still be in Mary's life. Mike is still helping Danny to find information on the woman his father was dating before he died.

After Ed's doctor warns him that his blood pressure is dangerously high, Ed becoms the victim of identity theft. Sam's half-brother visits. Mike borrows Ed's Aston Martin with unforseen consequences.

Sam's brother is staying longer than expected because he's having an affair with Monica. Danny tracks down the woman who appears on pictures with his father.

Danny imagines to be back in the 60s when the Montecito was called the Jubilee. Ed becomes the new president of the casino. He makes Danny the director of entertainment and Mike the head of security. Mary is a waitress who gets a promotion. Delinda opens a dress shop. And Sam starts out as a call girl.

A necklace with a priceless gemstone, the Star of Kashmir, is being stolen while on display in the Montecito.

Following Monica's sudden death, Danny becomes the main suspect. Danny and Casey arrives at the Montecito for a hostile takeover, but it appears that Monica's will leaves Montecito to a foundation for the blind. Mike is assaulted in the stairway after breaking up a fight, which leaves Danny, Ed and even Mary to find out whom could do something like that to Mike. Ed takes care of Monica's will, and her belongings.

A televised national poker tour comes to the Montecito. At the same time, Casey, not knowing what APAC means, lets the Porn industry host a convention at the Montecito. Additionally, to make up for this bad publicity, Casey orders a commercial to be done at the Montecito, with Ed as the face of the casino.

Real diamonds get stolen from the pool at Montecito when Lil' Flip is shooting a music video. Metro cannot be called in due to the jeweller's special request, and investigating gets harder. A guy plays suspiciously good at the craps table, claiming to have a gift to be able to win when he wants. Ed and Mike wants to go to the bottom of his true gift. Mike appears to be a stripper with quite a package, if one are to believe the flyers that are floating around at the casino.

Monica's old suite seems to be haunted, causing troubles with the new residents. Sam makes a bet with Paul Logan, a rival casino host - who's the best casino host/hostess there is? Delinda faces problem with the health inspector at Mystique, but seems wrongly treated. Meanwhile, Mary decides to take advantage of the ghost situation and starts a "Haunted Montecito Tour."

Almost three million dollars have disappeared from Montecito. The gaming commission has to clear Casey's licence and the missing money becomes an issue. Despite being dead, it seems Monica still gets Montecito in troubles. A live weather report is to be aired from inside the casino, when the weatherman gets an allergic reaction, allowing Mike to take his place for one night. Danny and Mike is to find the missing millions, and the thief, no matter if the thief is dead or not.

An urban legend becomes true when Danny finds a guest in an ice filled bathtub missing a kidney. To avoid bad press, the lawyers want to pay him for his silence, but Danny and Mike have other plans and start to investigate a possible scam. Ed helps Sam treat a whale who suffers from really sweaty hands, which is starting to scare the other guests away. Jimmie Johnson comes over to the Montecito to be the final judge of a car convention, in which Delinda for one is participating in.

Norma Pitts, one of Monica's friends, is at the Montecito. She finds a finger in the new buffet. Sam has to deal with a customer who doesn't want her as his host.

A chip thief who was caught by Mike and Danny claims that he met somebody who wants to blow up the Montecito. Wolfgang Puck and Gunther are having a cook-off. Sam hears about a masseur at the Montecito who offers "special treatments."

Mary is planning an expensive wedding for one of Sam's biggest clients. Mike and Danny investigate card counters.

Danny and Mike probe serial robberies in the casino's residential suites and also find time to serve as models for a charity calendar. Meanwhile, Jillian is alarmed when she discovers her marriage to Ed may have adversely affected Delinda. Mary deals with a hard to please European.

Romance begins to bloom between Danny and Delinda, to their utmost surprise. But keeping the relationship tight-lipped proves difficult, particularly when Jillian flies in Delinda's old college flame (Shawn Christian). Meanwhile, Casey organizes a paintball retreat for the department heads.

Ed and Jillian go to a spa. Danny and Mike are suspicious about one of Sam's whales. Derek and Delinda are getting serious.

Excitement's in the air at the Montecito when Olympic athlete Sasha Cohen stops by. Delinda gives Derek an answer to his marriage proposal. A couple big gamblers enlist Danny and Mike to investigate whether their spouses are cheating. Sam and Woody take off for a romantic weekend.

While Delinda is preparing to get married old romances resurface. Bachelor and Bachelorette Parties are being planned. Meanwhile Ed is being visited by his CIA past.