MacGyver and an old friend dash around the world searching for the artifacts necessary to locate the Holy Grail, just one step ahead of a ruthless man on the same trail.

Mac and a bounty hunter join forces with a bulldog named Frog to track down a Bulgarian defector who was the accidental witness at a murder and who is now being stalked by the killer, who needs a map she doesn't know she possesses.

During some tough negotiations between two neighbouring states, one side plants a sniper in the vicinity. When Mac discovers the sniper, he fights him, but loses the man and the accusations go out against Mac. Wounded and forced to run, he hides at a private girls' school, where one of the young ladies becomes his only hope to prevent further bloodshed.

MacGyver and an old friend discover a gang ripping off medical supplies from a Phoenix Foundation clinic in Asia, and an Amerasian son the friend never knew he had.

An old nemesis enlists MacGyver's help to rescue someone important to him—and she's scheduled to be executed during a Halloween Party put on by a professional assassination organization.

MacGyver takes off for Africa, where the youngest of the Colton brothers has decided to take on deadly rhino poachers single-handedly.

The Phoenix Foundation's purchase of a Nazi art treasure leads Mac to a holocaust survivor who claims family ownership of the painting, and to a group working to create their own ‘Aryan nation’.

MacGyver tries to help an old friend who believes her jealous twin sister is trying to kill her.

On Christmas Eve, MacGyver tries to help the priest of a poor church locate a stolen Madonna figure, help his friend Cynthia figure out how to keep the Challenger Club solvent and figure out a strange street woman who seems to have a miracle up her sleeve.

Exhausted MacGyver dreams he's a Civil War vet trying to claim a home in Montana that's threatened by a neighboring rancher who looks a lot like Pete Thornton. But this Pete has hired Murdoc to kill Mac...

MacGyver tries to inspire a promising but unmotivated high school student, despite the negative efforts of a cynical teacher and the boy's skeptical father.

MacGyver tries to help an environmentally active friend find out what happened to a company whistle-blower about to expose the illegal practices of a large logging firm.

MacGyver and a friend race with a group of dedicated guerillas to locate a valuable Incan treasure.

MacGyver, Dalton, and Thornton go undercover to expose a murderous money launderer.

Pete and Mac try to help when a Phoenix Foundation engineer is seduced and betrayed by a spy seeking her prototype for a new stealth technology for submarines.

A strange young woman gets Mac involved with a priceless violin and an eccentric maestro being sought by syndicate hoods.

MacGyver is reunited with Lisa, whose help cleared him of assassination charges in Switzerland, when a steel plant executive kidnaps her as revenge against her cold corporate-raider father.

MacGyver risks judicial displeasure when he breaks jury sequester to investigate the scene of a racially charged murder, and discovers evidence that drastically alters the interpretation of the facts.

Frantic with worry about his gravely-ill Grandpa Harry, MacGyver experiences a strange near-death phenomena, seeing his parents again, when he's injured by a man who's stolen an ancient Egyptian relic.